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U.S. health officials on Monday advised against travel to Canada, citing “very high” levels of the coronavirus in the country.

Canada joins scores of countries that the Centers for Disease Control and Prevention (CDC) has grouped under a Level 4 travel advisory, its most severe, including most of Europe and nations in southern Africa. The agency has also urged unvaccinated people to avoid travel to 54 additional nations, including Mexico – by far the top international destination for U.S. citizens last year, according to federal data. The CDC also issued a Level 4 warning for Curaçao on Monday.

New coronavirus cases have risen sharply in Canada in the past few weeks, according to a Johns Hopkins University tracker, as the omicron variant fuels a new global wave of infections.

“If you must travel to Canada, make sure you are fully vaccinated before travel,” the CDC said in its travel alert for Canada, which indicates high prevalence of the virus. “Because of the current situation in Canada, even fully vaccinated travelers may be at risk for getting and spreading COVID-19 variants.”